MLS Odds (United Kingdom)

18 upcoming matches and outright odds across 30 competitors.

OddsGuard delivers comprehensive real-time MLS odds comparison from leading bookmakers, ensuring you never miss the best value when betting on Major League Soccer. Our platform instantly aggregates odds across multiple operators, allowing you to spot the most profitable lines for match winners, goal totals, and futures markets with just a few clicks.

MLS has captured significant attention among United Kingdom football enthusiasts, particularly those drawn to the league's unique playoff format and the influx of European talent heading stateside. The regular season's conference-based structure, combined with the high-scoring nature of many fixtures, creates compelling betting opportunities that differ markedly from traditional European leagues. With designated player signings bringing world-class talent like Lorenzo Insigne and Giorgio Chiellini to North American pitches, MLS odds reflect an increasingly competitive and unpredictable championship.

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Upcoming Matches

Sunday

San Jose Earthquakes vs Seattle Sounders FC

Sun, Mar 15, 11:00 PM

BookmakerSan Jose EarthquakesDrawSeattle Sounders FC
Best Odds
4/1
Paddy Power
5/2
Sky Bet
22/25
Smarkets
Bet VictorBet Victor
18/523/104/5
Bet365Bet365
15/412/54/5
BoyleSportsBoyleSports
15/423/104/5
CasumoCasumo
15/412/577/100
GrosvenorGrosvenor
18/523/1077/100
SmarketsSmarkets
39/1012/522/25
Virgin BetVirgin Bet
18/523/1077/100
Paddy PowerPaddy Power
4/14/5
BetwayBetway
83/100
CoralCoral
23/10
LadbrokesLadbrokes
23/10
LeoVegasLeoVegas
7/2
LiveScore BetLiveScore Bet
18/5
Sky BetSky Bet
5/2

Saturday

Toronto FC vs Columbus Crew SC

Sat, Mar 21, 5:00 PM

BookmakerToronto FCDrawColumbus Crew SC
Best Odds
46/25
Smarkets
13/5
Paddy Power
34/25
Smarkets
Bet VictorBet Victor
7/412/513/10
Bet365Bet365
17/105/227/20
Betfair SportsbookBetfair Sportsbook
8/52/15/4
BetwayBetway
9/512/513/10
BoyleSportsBoyleSports
17/1012/56/5
CoralCoral
17/1023/105/4
LadbrokesLadbrokes
17/1023/105/4
Paddy PowerPaddy Power
17/1013/513/10
Sky BetSky Bet
8/512/55/4
SmarketsSmarkets
46/2549/2034/25

Philadelphia Union vs Chicago Fire

Sat, Mar 21, 8:30 PM

BookmakerPhiladelphia UnionDrawChicago Fire
Best Odds
6/5
Betway
5/2
Paddy Power
5/2
Betway
Bet VictorBet Victor
21/205/221/10
Bet365Bet365
101/1005/29/4
Betfair SportsbookBetfair Sportsbook
1/12/147/25
BetwayBetway
6/519/105/2
BoyleSportsBoyleSports
21/2011/521/10
CoralCoral
21/2011/521/10
LadbrokesLadbrokes
21/2011/521/10
Paddy PowerPaddy Power
11/105/29/4
Sky BetSky Bet
21/209/421/10
SmarketsSmarkets
11/1011/523/10

Nashville SC vs Orlando City SC

Sat, Mar 21, 10:00 PM

BookmakerNashville SCDrawOrlando City SC
Best Odds
63/100
Smarkets
333/100
Paddy Power
15/4
Paddy Power
Bet VictorBet Victor
3/53/17/2
Bet365Bet365
61/1003/17/2
Betfair SportsbookBetfair Sportsbook
53/1005/27/2
BetwayBetway
61/10016/5333/100
BoyleSportsBoyleSports
57/10016/516/5
CoralCoral
3/53/116/5
LadbrokesLadbrokes
3/53/116/5
Paddy PowerPaddy Power
3/5333/10015/4
Sky BetSky Bet
11/203/1333/100
SmarketsSmarkets
63/10016/518/5

Charlotte FC vs New York Red Bulls

Sat, Mar 21, 11:30 PM

BookmakerCharlotte FCDrawNew York Red Bulls
Best Odds
11/10
Betway
5/2
Bet365
53/20
Smarkets
Bet VictorBet Victor
1/15/29/4
Bet365Bet365
24/255/212/5
Betfair SportsbookBetfair Sportsbook
91/1002/121/10
BetwayBetway
11/102/113/5
BoyleSportsBoyleSports
91/1009/423/10
CoralCoral
19/2011/512/5
LadbrokesLadbrokes
19/2011/512/5
Paddy PowerPaddy Power
1/15/212/5
Sky BetSky Bet
19/2023/109/4
SmarketsSmarkets
26/2543/2053/20

Atlanta United FC vs D.C. United

Sat, Mar 21, 11:30 PM

BookmakerAtlanta United FCDrawD.C. United
Best Odds
97/100
Smarkets
13/5
Paddy Power
3/1
Bet365
Bet VictorBet Victor
91/10012/513/5
Bet365Bet365
43/5012/53/1
Betfair SportsbookBetfair Sportsbook
83/10021/105/2
BetwayBetway
19/2012/513/5
BoyleSportsBoyleSports
87/10012/513/5
CoralCoral
83/10023/1011/4
LadbrokesLadbrokes
83/10023/1011/4
Paddy PowerPaddy Power
9/1013/514/5
Sky BetSky Bet
83/10012/55/2
SmarketsSmarkets
97/10049/2011/4

Sunday

FC Dallas vs Houston Dynamo

Sun, Mar 22, 12:30 AM

BookmakerFC DallasDrawHouston Dynamo
Best Odds
6/5
Smarkets
27/10
Paddy Power
11/5
Smarkets
Bet VictorBet Victor
11/105/22/1
Bet365Bet365
21/205/221/10
Betfair SportsbookBetfair Sportsbook
1/121/1047/25
BetwayBetway
23/209/411/5
BoyleSportsBoyleSports
11/1012/519/10
CoralCoral
11/1023/102/1
LadbrokesLadbrokes
11/1023/102/1
Paddy PowerPaddy Power
11/1027/102/1
Sky BetSky Bet
21/205/219/10
SmarketsSmarkets
6/547/2011/5

Sporting Kansas City vs Colorado Rapids

Sun, Mar 22, 12:30 AM

BookmakerSporting Kansas CityDrawColorado Rapids
Best Odds
7/5
Betway
27/10
Bet365
21/10
Betway
Bet VictorBet Victor
13/1013/58/5
Bet365Bet365
27/2027/10157/100
Betfair SportsbookBetfair Sportsbook
6/521/103/2
BetwayBetway
7/519/1021/10
BoyleSportsBoyleSports
6/523/103/2
CoralCoral
13/1023/1081/50
LadbrokesLadbrokes
13/1023/1081/50
Paddy PowerPaddy Power
13/1013/517/10
Sky BetSky Bet
5/412/58/5
SmarketsSmarkets
67/5047/2049/25

Austin FC vs Los Angeles FC

Sun, Mar 22, 12:30 AM

BookmakerAustin FCDrawLos Angeles FC
Best Odds
3333/1000
Bet365
27/10
Paddy Power
22/25
Smarkets
Bet VictorBet Victor
29/105/24/5
Bet365Bet365
3333/100013/519/25
BetwayBetway
11/45/222/25
BoyleSportsBoyleSports
11/45/283/100
CoralCoral
14/55/23/4
LadbrokesLadbrokes
14/55/23/4
Paddy PowerPaddy Power
14/527/1017/20
Sky BetSky Bet
13/55/24/5
SmarketsSmarkets
29/1051/2022/25

St. Louis City SC vs New England Revolution

Sun, Mar 22, 12:30 AM

BookmakerSt. Louis City SCDrawNew England Revolution
Best Odds
22/25
Betway
3/1
Bet365
14/5
Paddy Power
Bet VictorBet Victor
4/514/513/5
Bet365Bet365
79/1003/127/10
BetwayBetway
22/2511/45/2
CoralCoral
4/511/45/2
LadbrokesLadbrokes
4/511/45/2
Paddy PowerPaddy Power
4/514/514/5
Sky BetSky Bet
3/413/513/5

Vancouver Whitecaps FC vs San Jose Earthquakes

Sun, Mar 22, 2:30 AM

BookmakerVancouver Whitecaps FCDrawSan Jose Earthquakes
Best Odds
57/100
Betway
7/2
Paddy Power
27/5
Smarkets
Bet VictorBet Victor
1/217/54/1
Bet365Bet365
23/503333/10009/2
BetwayBetway
57/10011/49/2
CoralCoral
1/216/54/1
LadbrokesLadbrokes
1/216/54/1
Paddy PowerPaddy Power
1/27/29/2
Sky BetSky Bet
11/2516/54/1
SmarketsSmarkets
14/2513/527/5

New York City FC vs Inter Miami CF

Sun, Mar 22, 5:00 PM

BookmakerNew York City FCDrawInter Miami CF
Best Odds
13/10
Ladbrokes
27/10
Bet365
19/10
Betway
Bet VictorBet Victor
6/513/57/4
Bet365Bet365
5/427/107/4
BetwayBetway
5/423/1019/10
CoralCoral
13/1012/58/5
LadbrokesLadbrokes
13/1012/58/5
Paddy PowerPaddy Power
5/427/109/5
Sky BetSky Bet
23/205/217/10
SmarketsSmarkets
29/259/443/25

FC Cincinnati vs CF Montreal

Sun, Mar 22, 5:00 PM

BookmakerFC CincinnatiDrawCF Montreal
Best Odds
7/10
Betway
3/1
Paddy Power
7/2
Paddy Power
Bet VictorBet Victor
67/10029/1016/5
Bet365Bet365
31/5029/103333/1000
BetwayBetway
7/1014/516/5
CoralCoral
67/10011/43/1
LadbrokesLadbrokes
67/10011/43/1
Paddy PowerPaddy Power
67/1003/17/2
Sky BetSky Bet
67/10011/43/1
SmarketsSmarkets
63/10013/531/10

Minnesota United FC vs Seattle Sounders FC

Sun, Mar 22, 6:30 PM

BookmakerMinnesota United FCDrawSeattle Sounders FC
Best Odds
2/1
Bet365
5/2
Paddy Power
69/50
Betway
Bet VictorBet Victor
9/523/1013/10
Bet365Bet365
2/112/523/20
BetwayBetway
9/511/569/50
CoralCoral
9/511/55/4
LadbrokesLadbrokes
9/511/55/4
Paddy PowerPaddy Power
47/255/213/10
Sky BetSky Bet
7/49/46/5
SmarketsSmarkets
44/2521/106/5

Portland Timbers vs LA Galaxy

Sun, Mar 22, 8:30 PM

BookmakerPortland TimbersDrawLA Galaxy
Best Odds
7/5
Betway
14/5
Paddy Power
81/50
Betway
Bet VictorBet Victor
69/5013/53/2
BetwayBetway
7/512/581/50
CoralCoral
13/1012/53/2
LadbrokesLadbrokes
13/1012/53/2
Paddy PowerPaddy Power
7/514/58/5
Sky BetSky Bet
13/105/229/20

Portland Timbers vs LA Galaxy

Sun, Mar 22, 8:30 PM

BookmakerPortland TimbersDrawLA Galaxy
Best Odds
27/20
Bet365
27/10
Bet365
3/2
Bet365
Bet365Bet365
27/2027/103/2

San Diego FC vs Real Salt Lake

Sun, Mar 22, 11:00 PM

BookmakerSan Diego FCDrawReal Salt Lake
Best Odds
57/100
Bet365
3/1
Bet365
15/4
Bet365
Bet365Bet365
57/1003/115/4

San Diego FC vs Real Salt Lake

Sun, Mar 22, 11:00 PM

BookmakerSan Diego FCDrawReal Salt Lake
Best Odds
61/100
Betway
16/5
Paddy Power
15/4
Bet Victor
Bet VictorBet Victor
57/1003/115/4
BetwayBetway
61/1003/17/2
CoralCoral
57/10029/107/2
LadbrokesLadbrokes
57/10029/107/2
Paddy PowerPaddy Power
3/516/515/4
Sky BetSky Bet
11/2029/10333/100
SmarketsSmarkets
27/5057/207/2

MLS Winner Odds

CompetitorBest Odds
Bet365
Inter Miami CF
13/8
Bet365
13/8
Los Angeles FC
2/1
Bet365
2/1
Vancouver Whitecaps FC
4/1
Bet365
4/1
San Diego FC
9/2
Bet365
9/2
Nashville SC
5/1
Bet365
5/1
New York City FC
11/2
Bet365
11/2
Seattle Sounders FC
7/1
Bet365
7/1
FC Cincinnati
9/1
Bet365
9/1
New York Red Bulls
14/1
Bet365
14/1
Philadelphia Union
14/1
Bet365
14/1
Columbus Crew SC
16/1
Bet365
16/1
Houston Dynamo
16/1
Bet365
16/1
LA Galaxy
16/1
Bet365
16/1
Charlotte FC
20/1
Bet365
20/1
Real Salt Lake
20/1
Bet365
20/1
San Jose Earthquakes
20/1
Bet365
20/1
Chicago Fire
33/1
Bet365
33/1
Colorado Rapids
33/1
Bet365
33/1
FC Dallas
33/1
Bet365
33/1
Minnesota United FC
33/1
Bet365
33/1
Toronto FC
33/1
Bet365
33/1
Atlanta United FC
40/1
Bet365
40/1
Austin FC
40/1
Bet365
40/1
D.C. United
40/1
Bet365
40/1
Orlando City SC
40/1
Bet365
40/1
New England Revolution
66/1
Bet365
66/1
Portland Timbers
66/1
Bet365
66/1
Sporting Kansas City
66/1
Bet365
66/1
CF Montreal
80/1
Bet365
80/1
St. Louis City SC
150/1
Bet365
150/1

MLS Betting Guide for United Kingdom

Understanding MLS odds requires familiarity with both American and fractional formats commonly used by bookmakers serving United Kingdom customers. Match winner markets (equivalent to 1X2 in European football) remain the most straightforward option, while Asian handicap betting proves particularly valuable given MLS's tendency toward high-scoring encounters. The league's playoff system also creates lucrative futures betting opportunities, with MLS Cup odds shifting dramatically as teams secure playoff positions during the regular season's final weeks.

Popular MLS betting markets extend beyond traditional match outcomes to include both teams to score, over/under goal totals, and first goalscorer options. The league's attacking philosophy and designated player rule often produce matches with 3+ goals, making totals betting especially appealing. Conference winner markets provide excellent value during mid-season, as the Eastern and Western Conference champions aren't always the teams with the highest regular season points totals.

When comparing MLS odds across different bookmakers, pay close attention to injury reports and international duty call-ups, which can significantly impact squad strength. Weather conditions also play a crucial role in outdoor stadiums, particularly during early season fixtures in northern markets like Toronto and Minnesota.

Can I bet on MLS playoffs from the United Kingdom?

Yes, most licensed bookmakers offer comprehensive MLS playoff betting, including match winners, series prices, and MLS Cup futures throughout the postseason.

What makes MLS betting different from Premier League wagering?

MLS features salary cap restrictions, designated player rules, and a playoff format that creates more unpredictable outcomes compared to traditional European league structures, often providing better value in underdog and futures markets.

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